The TX queue parameters control how packets are transmitted and retransmitted in the network, including timing for retries, backoff intervals, and queue timeouts. These parameters rely on the slot time, which is a critical timing unit used by the MAC protocol for collision avoidance and backoff calculations. Changing the slot time without updating the TX queue parameters can cause mismatches in timing, leading to inefficiencies, increased collisions, and reduced network performance. Proper synchronization ensures smooth and efficient medium access.